Target-Controlled Infusion

Target Controlled Infusion (TCI)

A comparison of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion for oocyte retrieval

OBJECTIVE To evaluate the effects of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion on hemodynamic parameters, pain, sedation, and recovery score during oocyte retrieval. METHODS Sixty-nine women were scheduled for oocyte retrieval. Target-controlled propofol infusion at an effect-site concentration of 1.5 μg/mL was instituted. The pat...

A target-controlled infusion regimen for reducing remifentanil-induced coughs

BACKGROUND This study evaluates the effectiveness of the target-controlled infusion (TCI) of remifentanil through stepwise increases in the effect-site concentration (C(eff)) in preventing coughs. METHODS In a preliminary study, we randomly selected 140 patients to receive remifentanil through two-step increases in C(eff) (1.0 ng/ml to 4.0 ng/ml: Group R(1-4); 2.0 ng/ml to 4.0 ng/ml: Group R(...

Performance of target-controlled sufentanil infusion in obese patients.

BACKGROUND Because obesity might affect pharmacokinetic parameters, the authors evaluated the accuracy of target-controlled sufentanil infusion in morbidly obese patients using a pharmacokinetic model usually applied to a normal-weight population. METHODS Target-controlled propofol and sufentanil coinfusions were administered to 11 morbidly obese patients (body mass index: 45.0 +/- 6.5 kg/m2 ...

Science vs supposition: the case of target-controlled propofol infusion.

Editor—I continue to be confounded by the use of target-controlled propofol infusion (TCI) dosing paradigm as an accepted basis for presenting the scientific study in anaesthesia journals without specific documentation of instantaneous and total dose infusion rates, in conjunction with body weight and duration of infusion at the study point. Although TCI may be utilitarian in the clinical admin...